繁體中文Preimplantation genetic testing (PGT)
PGT allows selection of normal embryos to be transferred to the patients who are at risk of severe genetic disorders and is an alternative to prenatal diagnosis.
It is indicated when the fetus is at risk of monogenic disorders, chromosomal abnormality (e.g. balanced translocation in the couple) or in women with advanced maternal age, recurrent implantation failure or recurrent pregnancy loss.
Gender selection for non-medical reasons is not allowed in Hong Kong.
We have recently upgraded our PGT platform to UniPGT-plus, making use of whole genome next generation sequencing to improve the accuracy of PGT.
| UniPGT-plus | |
|---|---|
| Aneuploidy | √ |
| Mosaicism | √ |
| Microdeletion/microduplication | √ |
| Contamination | √ |
| Haploidy / triploidy / polyploidy | √ |
| Uniparental disomy (isodisomy) | √ |
| Genetic analysis of 1PN/3PN embryo | √ |
| Kinship analysis | √ |