{"id":1153,"date":"2023-09-04T09:49:08","date_gmt":"2023-09-04T01:49:08","guid":{"rendered":"https:\/\/hkuivf.hku.hk\/?page_id=1153"},"modified":"2026-10-23T12:30:15","modified_gmt":"2026-10-23T04:30:15","slug":"genetic-testing-service","status":"publish","type":"page","link":"https:\/\/hkuivf.hku.hk\/en\/services\/genetic-testing-service\/","title":{"rendered":""},"content":{"rendered":"<p><\/p>\n<div style=\"font-family: -apple-system, BlinkMacSystemFont, 'Segoe UI', Roboto, 'Helvetica Neue', Arial, 'Noto Sans TC', 'Microsoft JhengHei', sans-serif; color: #000000; line-height: 1.6; max-width: 900px;\">\n<div style=\"font-size: 22px; font-weight: 800; margin-bottom: 24px; letter-spacing: -0.5px;\">Uni-RCS<\/div>\n<div style=\"font-size: 18px; font-weight: bold; margin-bottom: 24px;\">Reproductive Carrier Screening Panel<\/div>\n<div style=\"font-size: 18px; font-weight: bold; margin-bottom: 24px;\">474 Genes | Reproductive Risk Assessment<\/div>\n<div style=\"font-size: 18px; font-weight: normal; margin-bottom: 24px; line-height: 1.6;\">Uni-RCS is a carrier screening panel analysing 474 genes associated with autosomal recessive and X-linked disorders.<\/div>\n<div style=\"font-size: 18px; font-weight: normal; margin-bottom: 24px; line-height: 1.6;\">The panel includes all genes within the <span style=\"text-decoration: underline; text-underline-offset: 4px;\"><a style=\"color: #5c8491;\" href=\"https:\/\/pubmed.ncbi.nlm.nih.gov\/42141198\/\">Hong Kong Genome Project (HKGP) Chinese-specific Tier 1-3 gene list<\/a><\/span> and the <span style=\"text-decoration: underline; text-underline-offset: 4px;\"><a style=\"color: #5c8491;\" href=\"https:\/\/pubmed.ncbi.nlm.nih.gov\/34285390\/\">ACMG Pan-Ethnic Tier 1-3 Carrier Screening Panel<\/a><\/span>, providing comprehensive and population-relevant carrier screening for reproductive planning.<\/div>\n<div style=\"display: flex; justify-content: space-between; align-items: flex-end; margin-top: 32px; flex-wrap: wrap;\">\n<div style=\"flex: 1; min-width: 280px;\">\n<div style=\"font-size: 18px; font-weight: bold; display: flex; align-items: center; margin-bottom: 24px;\">Clinical Applications<\/div>\n<ul style=\"list-style: none; padding-left: 20px; margin: 0;\">\n<li style=\"font-size: 18px; font-weight: bold; margin-bottom: 16px; position: relative;\"><span style=\"position: absolute; left: -24px;\">\u2022<\/span>Preconception carrier screening<\/li>\n<li style=\"font-size: 18px; font-weight: bold; margin-bottom: 16px; position: relative;\"><span style=\"position: absolute; left: -24px;\">\u2022<\/span>Couple-based reproductive risk assessment<\/li>\n<li style=\"font-size: 18px; font-weight: bold; margin-bottom: 16px; position: relative;\"><span style=\"position: absolute; left: -24px;\">\u2022<\/span>Reproductive choice planning<\/li>\n<\/ul>\n<\/div>\n<div style=\"display: flex; flex-direction: column; align-items: center; text-align: center; margin-left: 40px; margin-top: 20px;\"><img decoding=\"async\" style=\"width: 180px; height: 180px; object-fit: contain;\" src=\"https:\/\/hkuivf.hku.hk\/wp-content\/uploads\/2026\/10\/picture-01-eng.png\" alt=\"Uni-RCS QR Code\" \/><\/div>\n<\/div>\n<\/div>\n<hr \/>\n<div style=\"font-family: -apple-system, BlinkMacSystemFont, 'Segoe UI', Roboto, 'Helvetica Neue', Arial, 'Noto Sans TC', 'Microsoft JhengHei', sans-serif; color: #000000; line-height: 1.6; max-width: 900px;\">\n<div style=\"font-size: 22px; font-weight: 800; margin-bottom: 24px; letter-spacing: -0.5px;\">Uni-RCS Plus<\/div>\n<div style=\"font-size: 18px; font-weight: bold; margin-bottom: 24px;\">Reproductive Genetics Panel<\/div>\n<div style=\"font-size: 18px; font-weight: bold; margin-bottom: 24px;\"><span class=\"s1\" style=\"font-family: -apple-system, BlinkMacSystemFont, 'Segoe UI', Roboto, 'Helvetica Neue', Arial, 'Noto Sans TC', 'Microsoft JhengHei', sans-serif;\">710 Genes | Carrier Screening | Fertility Genetics | ACMG Secondary Findings<\/span><\/div>\n<div style=\"font-size: 18px; font-weight: normal; margin-bottom: 24px; line-height: 1.6;\">Uni-RCS Plus is a comprehensive genetic screening panel designed for reproductive risk assessment and fertility genetics evaluation. The test analyses 710 unique genes, integrating carrier screening, fertility-associated genes, and medically actionable secondary findings in a single assay.<\/div>\n<div style=\"font-size: 18px; font-weight: normal; margin-bottom: 24px; line-height: 1.6;\">\n<p>The panel includes:<\/p>\n<ul style=\"list-style: none; padding-left: 20px; margin: 0;\">\n<li style=\"font-size: 18px; font-weight: bold; margin-bottom: 16px; position: relative;\"><span style=\"position: absolute; left: -24px;\">\u2022<\/span><span style=\"text-decoration: underline; text-underline-offset: 4px;\"><a style=\"color: #5c8491;\" href=\"#\">474 genes associated with autosomal recessive and X-linked disorders<\/a><\/span><\/li>\n<li style=\"font-size: 18px; font-weight: bold; margin-bottom: 16px; position: relative;\"><span style=\"position: absolute; left: -24px;\">\u2022<\/span>161 male fertility-related genes<\/li>\n<li style=\"font-size: 18px; font-weight: bold; margin-bottom: 16px; position: relative;\"><span style=\"position: absolute; left: -24px;\">\u2022<\/span>175 female fertility-related genes<\/li>\n<li style=\"font-size: 18px; font-weight: bold; margin-bottom: 16px; position: relative;\"><span style=\"position: absolute; left: -24px;\">\u2022<\/span>81 ACMG Secondary Findings v3.2 genes<\/li>\n<\/ul>\n<\/div>\n<div style=\"font-size: 18px; font-weight: normal; margin-bottom: 24px; line-height: 1.6;\">Uni-RCS Plus incorporates all genes included in the <a style=\"color: #5c8491;\" href=\"https:\/\/pubmed.ncbi.nlm.nih.gov\/42141198\/\">Hong Kong Genome Project (HKGP) Chinese-specific Tier 1-3 gene list<\/a> and the <a style=\"color: #5c8491;\" href=\"https:\/\/pubmed.ncbi.nlm.nih.gov\/34285390\/\">ACMG Pan-Ethnic Tier 1-3 Carrier Screening Panel<\/a>. The panel integrates the ACMG Secondary Findings v3.2 and dedicated male and female fertility panels, providing broad genetic coverage for reproductive and personal health assessment.<\/div>\n<div style=\"display: flex; justify-content: space-between; align-items: flex-end; margin-top: 32px; flex-wrap: wrap;\">\n<div style=\"flex: 1; min-width: 280px;\">\n<div style=\"font-size: 18px; font-weight: bold; display: flex; align-items: center; margin-bottom: 24px;\">Clinical Applications<\/div>\n<ul style=\"list-style: none; padding-left: 20px; margin: 0;\">\n<li style=\"font-size: 18px; font-weight: bold; margin-bottom: 16px; position: relative;\"><span style=\"position: absolute; left: -24px;\">\u2022<\/span>Preconception genetic screening<\/li>\n<li style=\"font-size: 18px; font-weight: bold; margin-bottom: 16px; position: relative;\"><span style=\"position: absolute; left: -24px;\">\u2022<\/span>Couple-based reproductive risk assessment<\/li>\n<li style=\"font-size: 18px; font-weight: bold; margin-bottom: 16px; position: relative;\"><span style=\"position: absolute; left: -24px;\">\u2022<\/span>Reproductive choice planning<\/li>\n<li style=\"font-size: 18px; font-weight: bold; margin-bottom: 16px; position: relative;\"><span style=\"position: absolute; left: -24px;\">\u2022<\/span>Causes of male and female infertility<\/li>\n<li style=\"font-size: 18px; font-weight: bold; margin-bottom: 16px; position: relative;\"><span style=\"position: absolute; left: -24px;\">\u2022<\/span>Personalized health management<\/li>\n<\/ul>\n<\/div>\n<div style=\"display: flex; flex-direction: column; align-items: center; text-align: center; margin-left: 40px; margin-top: 20px;\"><img decoding=\"async\" style=\"width: 180px; height: 180px; object-fit: contain;\" src=\"https:\/\/hkuivf.hku.hk\/wp-content\/uploads\/2026\/10\/picture-02-eng.png\" alt=\"Uni-RCS Plus QR Code\" \/><\/div>\n<div style=\"font-size: 18px; font-weight: normal; margin-top: 24px; line-height: 1.6;\"><em><strong>Clinical Limitations:<\/strong> This test does not detect all genetic conditions or all types of genomic variants. Results should be interpreted in conjunction with clinical findings, family history, and genetic counselling.<\/em><\/div>\n<\/div>\n<\/div>\n<p><\/p>","protected":false},"excerpt":{"rendered":"<p>Uni-RCS Reproductive Carrier Screening Panel 474 Genes | Reproductive Risk Assessment Uni-RCS is a carrier screening panel analysing 474 genes associated with autosomal recessive and<\/p>\n","protected":false},"author":1,"featured_media":0,"parent":151,"menu_order":5,"comment_status":"closed","ping_status":"closed","template":"","meta":{"footnotes":""},"class_list":["post-1153","page","type-page","status-publish","hentry"],"_links":{"self":[{"href":"https:\/\/hkuivf.hku.hk\/en\/wp-json\/wp\/v2\/pages\/1153","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/hkuivf.hku.hk\/en\/wp-json\/wp\/v2\/pages"}],"about":[{"href":"https:\/\/hkuivf.hku.hk\/en\/wp-json\/wp\/v2\/types\/page"}],"author":[{"embeddable":true,"href":"https:\/\/hkuivf.hku.hk\/en\/wp-json\/wp\/v2\/users\/1"}],"replies":[{"embeddable":true,"href":"https:\/\/hkuivf.hku.hk\/en\/wp-json\/wp\/v2\/comments?post=1153"}],"version-history":[{"count":30,"href":"https:\/\/hkuivf.hku.hk\/en\/wp-json\/wp\/v2\/pages\/1153\/revisions"}],"predecessor-version":[{"id":1386,"href":"https:\/\/hkuivf.hku.hk\/en\/wp-json\/wp\/v2\/pages\/1153\/revisions\/1386"}],"up":[{"embeddable":true,"href":"https:\/\/hkuivf.hku.hk\/en\/wp-json\/wp\/v2\/pages\/151"}],"wp:attachment":[{"href":"https:\/\/hkuivf.hku.hk\/en\/wp-json\/wp\/v2\/media?parent=1153"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}